Preventing NAD+ Depletion Protects Neurons against Excitotoxicity
نویسندگان
چکیده
منابع مشابه
Ciliary Neurotrophic Factor Protects Striatal Neurons against Excitotoxicity by Enhancing Glial Glutamate Uptake
Ciliary neurotrophic factor (CNTF) is a potent neuroprotective cytokine in different animal models of glutamate-induced excitotoxicity, although its action mechanisms are still poorly characterized. We tested the hypothesis that an increased function of glial glutamate transporters (GTs) could underlie CNTF-mediated neuroprotection. We show that neuronal loss induced by in vivo striatal injecti...
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ژورنال
عنوان ژورنال: Annals of the New York Academy of Sciences
سال: 2008
ISSN: 0077-8923
DOI: 10.1196/annals.1427.028